Donald E. Dupuis, MD, FACS

General Surgery

About Us

General Surgeon

Dr. Donald Dupuis has led Copley Hospital’s General Surgery program since 2015. He has extensive experience with advanced laparoscopic procedures and trauma. He enjoys working with his patients and their referring physicians to do what is best for the patient. A graduate of the University of Vermont School of Medicine, he pursued his medical degree after working as an engineer. He did his general surgery residency at the Lahey Clinic in Burlington, MA. Previously, he had served at Cheshire Medical Center/Dartmouth-Hitchcock Medical Center in Keene, NH.

Dr. Dupuis spends his free time with his wife and two children. You will find him coaching soccer, skiing cross country and downhill, fishing, and sailing.

Watch video introduction of Dr. Dupuis here.

Campus Map


American College of Surgeons
Society of American Gastrointestinal and Endoscopic Surgeons

Education + Clinical Experience

Medical Degree, Surgery Major: University of Vermont College of Medicine, 2001
Masters of Science, Biomedical Engineering: University of Vermont, 1996,
Bachelor of Science, Mechanical Engineering: University of Colorado, 1991
Board Certification, General Surgery: American Board of Surgery, 2007

Cheshire Medical Center, Keene, NH, Attending General Surgeon, 2006-2015
Lahey Clinic, Burlington, MA, General Surgery Resident, 2003-2006
Trauma & Critical Care at Shock Trauma, MD
Virginia Mason Hospital, Seatle, WA, General Surgery Resident, 2001-2003
Harborview Medical Center, WA, Trauma and Critical Care
University of Vermont College of Medicine, Senior Research Scientist, 1996-1997
ERM-West, Los Angeles, CA and San Francisco, Project Manager/ Environmental Engineer, 1991-1994
Unysis CAD-CAM, Boulder, CO, Software Developer, 1989-1991
Rocky Mountain Bicycles, Boulder, CO, Bicycle Mechanic, 1985-1990
Mayflower Builders, Orleans, MA, Carpenter, 1985-1987
Pacific Designs, San Diego, CA, Surfboard Maker, 1983-1985


Dupuis, D.E., Beynnon, B.D., Richard, M.J., Novotny, J.E., Skelly, J.M., & Cooper, S.M. Precision and accuracy of joint space width measurements of the medial compartment of the knee using standardized MTP semi-flexed radiographs. Osteoarthritis and Cartilage 2003, 11(10):716-724. Palmiter, K.A., Dupuis, D.E., Alpert,N.R., Warshaw, D.M. Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms. Journal of Physiology 1999 Sep., 519(Pt 3):669-678. Tyska, M.J., Dupuis, D.E., Guilford, W.H., Waller, G.S., Trybus, K.M., Warshaw, D.M., & Lowey, S. The two heads of myosin cooperate to generate force and motion. Proc. Natl. Acad. Sci. USA 1999 Apr., 96(8):4402-7. Dupuis, D.E., Guilford, W.H., Wu, J., & Warshaw, D.M. Actin filament mechanics in the laser trap. Journal of Muscle Research and Cell Motility, 1997 Mar., 18(1), 17-30. Guilford, W.H., Dupuis, D.E., Kennedy, G., Wu, J., Patlack, J.B., & Warshaw, D.M. Smooth and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap. Biophysical Journal, 1997 Feb., 72, 1006-1021.


Dupuis, E.E., Bariatric Suergery at a Community Hospital. Grand Rounds. Brattleboro Memorial Hospital. Brattleboro, Vermont. September, 2012. Dupuis, D.E., Bariatric Surgery in Community Hospitals. Grand Rounds. Monadnock Community Hospital, Peterborough, New Hampshire. April, 2011. Dupuis, D.E., Bariatric Surgery and the Laparoscopic Adjustable Gastric Band. Grand Rounds. Cheshire Medical Center, Keene, New Hampshire. August, 2009. Dupuis, D.E., Sentineal Lymph Node Biopsy. Grand Rounds. Springfield Hospital, Springfield Vermont. May, 2007. Dupuis, D.E., Cross, S.M., Wei, J.P., Brams, D.M. Directed parathyroidectomy using preoperative and intraoperative localization facilitates unilateral exploration for cure of primary hyperparathyroidism. Poster session. New England Surgical Society Annual Meeting, Summer 2005. Dupuis, D.E., Holmes, J.H., Biehl, T.R., & Ryan, J.A. Laparoscopic resection of pedunculated hepatic tumors at Virginia Mason Medical Center. Podium session. ACS Washington State Chapter Summer Meeting, Summer 2002. Dupuis, D.E., Holmes, J.H., & Thirlby, R.C. GI Bleeding in Maffucci’s Syndrome. Podium session. Seattle Surgical Society Winter Meeting, Winter 2002. Dupuis, D.E., Guildford,W.H., Wu, J., & Warshaw, D.M. Actin filaments mechanics in the laser trap. Poster. Biophysical Society Annual Meeting, 1996.

  • Type Of Provider : Physician
  • Practice Name : Copley Hospital Multi-Specialty Clinic
  • General Surgery